1. Organisation of the eukaryotic cell. 2. Structure and composition of the plasma membrane. Transport of molecules across the membrane. 3. Extracellular matrix. Cell attachment and adhesion. 4. Introduction to intracellular compartments and protein transit. Nucleus. Cytosol. Endoplasmic reticulum. Golgi apparatus. Endosomes, lysosomes, vacuoles and peroxisomes. Vesicular traffic. Mitochondria. Microfilaments. Microtubules. Intermediate filaments. 5. Cell signalling. 6. Gene expression. Synthesis and processing of messenger RNAs. Post-translational modifications. Export of messengers from the nucleus to the cytoplasm. 7. Molecular machinery of translation. Aminoacylation reaction of tRNAs. Structure and assembly of ribosomes. 8. Translation of messengers. Initiation, elongation and termination factors and complexes Post-transcriptional control mechanisms. Global regulation of protein synthesis 9. Post-translational processes. Protein folding, modifications, sorting and degradation. 10. Cell cycle.

Classroom lectures. Face-to-face classes: reduced (workshops, seminars, case studies). Student individual work. Laboratory session. Final exam. Seminars and lectures supported by computer and audiovisual aids. Practical learning based on cases and problems, and exercise resolution. Individual and group or cooperative work with the option of oral or written presentation. Individual and group tutorials to resolve doubts and queries about the subject. Internships and directed laboratory activities.