Checking date: 20/06/2022

Course: 2022/2023

Fundamentals of tissue engineering and regenerative medicine
Study: Bachelor in Engineering Physics (363)

Coordinating teacher: GUERRERO ASPIZUA, SARA

Department assigned to the subject: Department of Bioengineering and Aerospace Engineering

Type: Electives
ECTS Credits: 6.0 ECTS


Requirements (Subjects that are assumed to be known)
It is desirable, but not required, to have a good previous background on: - Physics - Chemistry - Biology
Skills and learning outcomes
Description of contents: programme
Obtain an overview of tissue engineering in clinical medicine and biomedical research Understand the role of emerging technologies and engineering and life science disciplines in tissue engineering 1) Review of current status of tissue engineering and regenerative medicine Introduction to TE and overview of course objectives 2) Tissues morphological and functional units Organization of cell into higher ordered structures Dynamics of Cell-ECM Interactions Analysis of the physicochemical processes that affect limit and control cells and tissues function. - Epithelial Tissue, Connective Tissue, Muscular Tissue and Nervous Tissue 3) Systems and Organs: morphological and functional units Structural and dynamic interactions between mesenchyme and parenchyma The role of tissue microenvironment, extracellular matrix and communication by growth factors 4) Tegumentary System 5) Designing tissue functional units Stem cells and Genetic Engineering 6) Seminars on tissue recognition using virtual microscope. 7) "SPOC" about tissue engineering and regenerative medicine that wil firm up the continuous evaluation contents. LABORATORY EXPERIMENTS: (Every student will perform 15 hours of practical sessions in UC3M bioengineering laboratories) a. Use of conventional microscopy for the understanding of tissue structure. b. Understand microscopic organization of Tissues into Organs and systems. c. Tissue observation and image capture. Tissue engineering. d. Histology as a diagnostic tool. e. Use of Immunohistochemical techniques
Learning activities and methodology
AF1. THEORETICAL-PRACTICAL CLASSES. Knowledge and concepts students mustacquire. Receive course notes and will have basic reference texts.Students partake in exercises to resolve practical problems AF2. TUTORING SESSIONS. Individualized attendance (individual tutoring) or in-group (group tutoring) for students with a teacher.Subjects with 6 credits have 4 hours of tutoring/ 100% on- site attendance. AF3. STUDENT INDIVIDUAL WORK OR GROUP WORK.Subjects with 6 credits have 98 hours/0% on-site. AF8. WORKSHOPS AND LABORATORY SESSIONS. Subjects with 3 credits have 4 hours with 100% on-site instruction. Subjects with 6 credits have 8 hours/100% on-site instruction. AF9. FINAL EXAM. Global assessment of knowledge, skills and capacities acquired throughout the course. It entails 4 hours/100% on-site AF8. WORKSHOPS AND LABORATORY SESSIONS. Subjects with 3 credits have 4 hours with 100% on-site instruction. Subjects with 6 credits have 8 hours/100% on-site instruction. MD1. THEORY CLASS. Classroom presentations by the teacher with IT and audiovisual support in which the subject`s main concepts are developed, while providing material and bibliography to complement student learning MD2. PRACTICAL CLASS. Resolution of practical cases and problem, posed by the teacher, and carried out individually or in a group MD3. TUTORING SESSIONS. Individualized attendance (individual tutoring sessions) or in-group (group tutoring sessions) for students with teacher as tutor. Subjects with 6 credits have 4 hours of tutoring/100% on-site. MD6. LABORATORY PRACTICAL SESSIONS. Applied/experimental learning/teaching in workshops and laboratories under the tutor's supervision.
Assessment System
  • % end-of-term-examination 60
  • % of continuous assessment (assigments, laboratory, practicals...) 40
Basic Bibliography
  • Lanza RP, Langer R, Vacanti J. Principles of Tissue Engineering. . Third edition. Academic Press. 2007
  • Saltzman MW. Tissue Engineering: Engineering Principles for the Design of Replacement Organs and Tissues. Oxford University Press. 2004

The course syllabus may change due academic events or other reasons.