Checking date: 12/02/2024

Course: 2023/2024

Biophysics 1: Molecular, Cell and Tissue Physical Biology
Bachelor in Engineering Physics (Plan: 434 - Estudio: 363)

Coordinating teacher: MEDRAÑO FERNANDEZ, IRIA

Department assigned to the subject: Bioengineering Department

Type: Compulsory
ECTS Credits: 6.0 ECTS


Requirements (Subjects that are assumed to be known)
Skills and learning outcomes
CB1. Students have demonstrated possession and understanding of knowledge in an area of study that builds on the foundation of general secondary education, and is usually at a level that, while relying on advanced textbooks, also includes some aspects that involve knowledge from the cutting edge of their field of study. CB2. Students are able to apply their knowledge to their work or vocation in a professional manner and possess the competences usually demonstrated through the development and defence of arguments and problem solving within their field of study. CB3. Students have the ability to gather and interpret relevant data (usually within their field of study) in order to make judgements which include reflection on relevant social, scientific or ethical issues. CB4. Students should be able to communicate information, ideas, problems and solutions to both specialist and non-specialist audiences. CB5. Students will have developed the learning skills necessary to undertake further study with a high degree of autonomy. CG2. Learn new methods and technologies from basic scientific and technical knowledge, and being able to adapt to new situations. CG3. Solve problems with initiative, decision making, creativity, and communicate and transmit knowledge, skills and abilities, understanding the ethical, social and professional responsibility of the engineering activity. Capacity for leadership, innovation and entrepreneurial spirit. CG5. Use the theoretical and practical knowledge acquired in the definition, approach and resolution of problems in the framework of the exercise of their profession. CE10. Know and describe in a general way the structure of living beings at the molecular, cellular, tissue and systemic levels, as well as to analyze the limitations imposed by physical laws on the development of biological systems and biological solutions to engineering problems. CT1. Work in multidisciplinary and international teams as well as organize and plan work making the right decisions based on available information, gathering and interpreting relevant data to make judgments and critical thinking within the area of study. RA1. To have acquired sufficient knowledge and proved a sufficiently deep comprehension of the basic principles, both theoretical and practical, and methodology of the more important fields in science and technology as to be able to work successfully in them. RA2. To be able, using arguments, strategies and procedures developed by themselves, to apply their knowledge and abilities to the successful solution of complex technological problems that require creating and innovative thinking. RA3. To be able to search for, collect and interpret relevant information and data to back up their conclusions including, whenever needed, the consideration of any social, scientific and ethical aspects relevant in their field of study. RA6. To be aware of their own shortcomings and formative needs in their field of specialty, and to be able to plan and organize their own training with a high degree of independence.
Description of contents: programme
1. Regulation of Gene Expression. From genes to proteins. 2. Biosignaling. 3. Regulation of the Cell Cycle 4. Oncogenes, Tumor Suppressor Genes, and Programmed Cell Death 5. Membrane Structure and Function. Channels and Transporters. Regulation of Membrane Transport of Proteins and Signaling Receptors. 6. The Cell Cytoskeleton. Cell Mechanics. Mechanotransductio 7. Molecular Machines, Motors, and Nanoscale Biophysics. Biophysics of molecular motors (cytoskeletal and non-cytoskeletal) 8. Energy Generation in Mitochondria and Chloroplasts 9 Principles of Tissue Organization Laboratory practices: 1. Bacterial transformation and isolation of DNA plasmids 2. Human cell culture techniques
Learning activities and methodology
THEORETICAL-PRACTICAL CLASSES. In these lectures, the knowledge and concepts that students must acquire during the lessons. They will receive the course notes and basic reference texts. Students will share exercises to resolve practical problems and participate in master lectures. Practical lectures will be imparted in reduced groups. TUTORING SESSIONS. Individualized attendance (individual tutoring) or in-group (group tutoring) is available for any student upon request. STUDENT INDIVIDUAL WORK OR GROUP WORK. LABORATORY PRACTICAL SESSIONS. Applied/experimental learning/teaching in workshops and laboratories in-site under a tutor's supervision.
Assessment System
  • % end-of-term-examination 42
  • % of continuous assessment (assigments, laboratory, practicals...) 58

Calendar of Continuous assessment

Basic Bibliography
  • Bruce Alberts et al. Essential Cell Biology. Garland Publishing, Inc. 4th and 5th ed. 20202
  • Harvey Lodish et al. Molecular Cell Biology. Ed. Freeman and Company, New York.. 5th Edition
  • J. Sambrook, E.F. Fritash and T. Maniatis. Molecular Cloning: A laboratory Manual. Ed. Cold Spring Harbour Press.. 3rd Edition
  • Jennie P. Mather and David Barned. Animal Cell Culture Methods. Ed. Associated Press..
Additional Bibliography
  • Bruce Alberts et al. Molecular Biolgy of the Cell. Garland Publishing, Inc. New York and London. 5th Edition
  • Bruce Alberts et al. Molecular Biology of the Cell. Garland Science. 6th ed.
  • Lizabeth A. Allison. Fundamental Molecular Biology. Ed. Wiley-Balckwell.

The course syllabus may change due academic events or other reasons.