Checking date: 09/06/2021

Course: 2021/2022

Biomedical applications of nanotechnology
Study: Bachelor in Biomedical Engineering (257)

Coordinating teacher: MUÑOZ BARRUTIA, MARIA ARRATE

Department assigned to the subject: Department of Bioengineering and Aerospace Engineering

Type: Electives
ECTS Credits: 6.0 ECTS


Requirements (Subjects that are assumed to be known)
Students are strongly advised to have completed the subjects Chemistry, Materials Science and Engineering, Introduction to the design of medical instrumentation, Signals and systems and Introduction to Biomaterials.
The students will learn the basic principles of nanotechnology applied to biomedical problems in lectures and team work activities on reviewing of articles and practices in the laboratory. The course will focus on the design of devices based on nanotechnologies and the preparation of nanoparticles. It will also address the clinical application of these technologies in diagnosis (including imaging) and therapy, and its application in biomedicine. Students will familiarize themselves with the main techniques for the synthesis, characterization and biofunctionalization of the most common nanomaterials and their use in biometric devices or as contrast agents for diagnosis and therapy.
Skills and learning outcomes
Description of contents: programme
1.- Introduction to nanotechnology 2.- Imaging and characterizing the nanoscale 3.- Nanosensors for clinical applications 4.- Imaging nanodevices 5.- Nanodevices for manipulation of cells and biomolecules 6.- Nanoparticles for drug and gene delivery 7.- Modification and functionalization of nanoparticles for diagnosis and therapy 8.- Potential use of DNA for electronic and computer applications 9.- Safety and toxicity concerns of nanosystems Lab practices The dates will be announced early in the course. Practices will cover preparation of liposomes, synthesis of gold nanomaterials, gold nanoparticles-based sensors, design and characterisation of nanotechnology based sensors, and electronics for nanotechnology.
Learning activities and methodology
Each section of the program will be divided into lectures and practical sessions or seminars. The teaching methodology is based on master classes that introduce the fundamental concepts, seminars in which examples are illustrated in detail, and practical sessions in the laboratory. Students are required to read the assigned documentation prior to conferences and seminars. The lectures will be used to highlight and clarify some difficult or interesting points of the corresponding lesson. The seminars will be devoted mainly to the interactive discussion with the students and to conduct partial exams. The tutoring regime will be published in Aula Global.
Assessment System
  • % end-of-term-examination 40
  • % of continuous assessment (assigments, laboratory, practicals...) 60
Calendar of Continuous assessment
Basic Bibliography
  • BS Murty, P Shankar, B Raj, BB Rath, J Murday. Textbook of Nanocience and Nanotechnology. Springer University Press. 2013
  • C. Sharma. Drug Delivery Nanosystems for Biomedical Applications. Elsevier. 2014
Additional Bibliography
  • A. Offenhäusser, R. Rinaldi (Editors). Nanobioelectronics - for Electronics, Biology and Medicine. Nanostructure Science and Technology Series, Springer. 2009
  • A. P. Lee, L. James Lee (Editors). Biological and Biomedical Nanotechnology. Volume I, Biological and Biomedical Nanotechnology, Springer. 2006
  • Kevin C. Honeychurch (Editor. Nanosensors for Chemical and Biological Applications: Sensing with Nanotubes, Nanowires and Nanoparticles. Woodhead Publishing. 2014
  • Mauro Ferrari, Ph.D., Editor-in-Chief.. BioMEMS and Biomedical Nanotechnology. Vol. 1 Biological and Biomedical Nanotechnology. Springer. 2006
  • Paras N Prasad. Introduction to Nanomedicine and Nanobioengineering: Transforming Healthcare with Nanotechnology. John Wiley and Sons. 2012
  • Rajaventhan Srirajaskanthan, M.D.,Victor R. Preedy, Ph.D. Nanomedicine and Cancer. CRC Press. 2012
  • Vijay K. Varadan,LinFeng Chen,Jining Xie. Nanomedicine: Design and Applications of Magnetic Nanomaterials, Nanosensors . John Wiley and Sons. 2008

The course syllabus may change due academic events or other reasons.