It is strongly advised to have completed Cell and Molecular Biology, Biochemistry, Bioinformatics.

Fundamental knowledge and capabilities developed by cellular engineering scientists allows us to move beyond toward systematic mechanisms for predictable modulation of cell proliferation, migration, communication, and the production of small molecules and biologics. Modern biomedical science includes Systems Biology and Synthetic Biology, two new and complementary fields that constitute the basis of innovation. In this course, students will learn about the foundational technologies and theory behind engineering biology. Students will study strategies for engineering cellular and molecular systems as well as, will explore current and future applications for synthetic biology and system biology approaches. Students will study how to build novel synthetic biological systems that solve practical biomedical problems. They will incorporate elements from many different disciplines including chemistry, biology, mathematics, physics and engineering.

Gene and protein sequencing, gene expression analysis, protein expression and interaction analysis, genomic and proteomic analysis . protein-protein Interaction networks, metabolic networks and disease networks, quantitative tissue analysis, modeling biological systems: synthetic biology circuits, data analysis techniques and clinical computing interfaces. The course is divided mainly in two parts: SYSTEMS BIOLOGY AND OMIC TECHNOLOGIES: - Fundamentals of genomics, proteomics and metabolomics - How do normal cellular functions such as cellular division, cell activation, differentiation, and apoptosis emerge from the interaction of genes - How to examine whole cell functions corresponding to observable phenotypes. - How to generate network reconstructions, followed by the synthesis of in silico models describing functionalities. - Systems Analysis of Complex Diseases. - Systems Pharmacology: Understanding Drug Action from a System Perspective. - Systems Pharmacogenomics: Personalized medicine. SYNTHETIC BIOLOGY: - Design and construction of new biological parts, devices, and systems, and the re-design of existing natural biological system for better application. - Build artificial biological systems for engineering applications. - Draw powerful techniques for the rapid assembly of DNA. - Engineer biological system: modify the behaviour of organisms and engineer them to perform new tasks. Create bioengineered microorganisms that can produce pharmaceuticals and repair damaged genes.

The program will be divided into master classes and computer practical classes (cases). Students are required to read or resolve assigned chapters, articles, problems, etc., before the corresponding classes. The seminars will contain the discussion of relevant scientific articles and problems that will be presented by the students.