Checking date: 05/07/2021


Course: 2021/2022

Introduction to Biomaterials
(15553)
Study: Bachelor in Biomedical Engineering (257)


Coordinating teacher: VELASCO BAYON, DIEGO

Department assigned to the subject: Department of Bioengineering and Aerospace Engineering

Type: Compulsory
ECTS Credits: 6.0 ECTS

Course:
Semester:




Requirements (Subjects that are assumed to be known)
Cell and Molecular Biology Biochemistry
Objectives
This course is designed to provide a comprehensive understanding of the multidisciplinary field of biomaterials, focusing on the biological responses to materials and the clinical context of their use. Through lectures, paper reviews, in class discussions and invited lectures, students will be introduced to the Biomaterials Science and the physiological interactions between body environment and biomaterials. Students will be required to acquire understanding and expertise from analysis of primary literature and will complete group presentations on the status of state-of-the-art biomaterial applications, including medical implants, artificial organs, and scaffolds for tissue engineering.
Skills and learning outcomes
Description of contents: programme
This course is intended to provide a general understanding of the multidisciplinary field of biomaterials. Specifically, different types of biomaterials and the body¿s natural responses to biomaterial implantation will be studied. In addition, biomedical applications of biomaterials as well as design and development of commercial products will be addressed. 1. Introduction to Biomaterials. Basic concepts 2. Polymers and hydrogels for biomedical applications 3. Ceramics for biomedical applications 4. Biomaterial degradation 5. Designing biomaterials for 3D printing 6. Surface modification of biomaterials 7. Extracellular matrix-based biomaterials 8. Biomaterial implantation: acute inflammation and wound healing 9. Immune response to biomaterials 10. Infection, tumorigenesis and calcification of biomaterials 11. Blood-biomaterial interactions
Learning activities and methodology
The program will be divided into master classes (lectures) and discussion/problem classes (seminars). For specific subjects, there will be invited lectures given by prestigious professionals in the field. The topics covered by the invited speakers are part of the subject and will be evaluated in the continuous evaluation blocks and in the final exam as well. Students may be required to read assigned chapters/articles before the lectures and seminars. In the discussion classes, relevant scientific articles and problems will be presented and discussed by the students and the teaching team.
Assessment System
  • % end-of-term-examination 29
  • % of continuous assessment (assigments, laboratory, practicals...) 71
Calendar of Continuous assessment
Basic Bibliography
  • Chee Kai Chua, Wai Yee Yeong. Bioprinting: Principles and Applications. World Scientific Publishing Company. 2015
  • David Williams. Essential Biomaterials Science. Cambridge University Press. 2014
  • Jason A. Burdick and Robert L. Mauck. Biomaterials for Tissue Engineering Applications: A Review of the Past and Future Trends. Springer Verlag. 2011
  • Johnna S. Temenoff and Antonios G. Mikos. Biomaterials: The Intersection of Biology and Materials Science. Prentice Hall. 2009
Additional Bibliography
  • Abul K. Abbas, Andrew H. Lichtman and Shiv Pillai. Cellular and Molecular Immunology. Saunders. 2011
  • Buddy D. Ratner, Allan S. Hoffman, Frederick J. Schoen and Jack E. Lemons. Biomaterials Science: An Introduction to Materials in Medicine. Academic Press . 2012
  • Clark R.A.F. and Henson P.M. . The Molecular and Cellular Biology of Wound Repair. Plenum Press. 1996
  • Kay C. Dee, David A. Puleo and Rena Bizios. An Introduction to Tissue-Biomaterial Interactions. Wiley-Liss. 2002
  • María Vallet-Regí. Bio-Ceramics with Clinical Applications. Wiley. 2014

The course syllabus may change due academic events or other reasons.